Objective To establish a simple and efficient method for determination of dissociate formaldehyde in cosmetics samples by derivatization-headspace-gas chromatography, and to meet requirements of daily inspections.
Methods Dissociate formaldehydes were extracted by liquid-liquid extraction technique using water and derivatized with pentafluorop henylhydrazine (PFPH). The derivatives were separated by gas chromatography and measured by hydrogen flame ionization detector.
Results The derivatization reaction effectively removed interferences. The spiked concentrations of this method were 8.0-40.0 mg/kg. The average recovery was 106% and the relative standard deviation (RSD) ranged from 1.8% to 5.2% (n=6). The detection limit was 0.6 mg/kg.
Conclusion This method for dissociate formaldehyde determination in cosmetics is simple, quick and accurate. It can meet routine laboratory testing requirements.
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