Objective To explore the occupational risk factors of bladder cancer in petrochemical enterprises.
Methods In this matched case control study, 21 bladder cancer cases were enrolled, each matched with 4 controls on gender, ethnicity and age (within 3 years). Information about potential bladder cancer risk factors was collected through a self-designed questionnaire. Conditional logistic regression analysis was conducted with SAS 8.0 and Excel 2003.
Results Univariate analysis showed that workers with chemical exposure was 8 times (95% confidence interval:1.465-43.678) as likely to develop bladder cancer as those without, and longer working years was associated with higher risks of bladder cancer also. Multivariate analysis also validated that job with chemical processing in petrochemical enterprises was a risk factor of bladder cancer.
Conclusion Bladder cancer is occupationally related to job position in chemical work and extended length of exposure.