Objective To investigate the risk factors which have effects on birth defects in Minhang District of Shanghai.
Methods A case-control study was conducted by either home visit or informing the respondents to come to accept unified epidemiological investigations.
Results The results of univariate logistic regression analysis showed that the occurrence of birth defects was correlated with 8 factors including maternal occupation, per capita household income, previous history of birth defects, twins or multiple births, supplement of essential nutrients during pregnancy, severe emotional events, husband's drinking habits before wife's pregnancy, and time to move in a house after decoration (P<0.05). Multivariate logistic regression analysis showed that severe emotional events and previous history of birth defects entered the model.
Conclusion The occurrence of birth defects is associated with many factors. Targeted measures against these risk factors could be effective in reducing the in cidence of birth defects.
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