TAN Qiang , CHEN Bo-ning , YU Ying-ying , WANG Mao , SONG Hong . Study on the Relationship between Traffic Artery Air Pollution and Urine 8-OH-dG Level in Schoolchildren[J]. Journal of Environmental and Occupational Medicine, 2011, 28(2): 63-67.
Citation: TAN Qiang , CHEN Bo-ning , YU Ying-ying , WANG Mao , SONG Hong . Study on the Relationship between Traffic Artery Air Pollution and Urine 8-OH-dG Level in Schoolchildren[J]. Journal of Environmental and Occupational Medicine, 2011, 28(2): 63-67.

Study on the Relationship between Traffic Artery Air Pollution and Urine 8-OH-dG Level in Schoolchildren

More Information
  • Corresponding author:

    SONG Hong ,Email:songhong@mail.sysu.edu.cn

  • Received Date: March 15, 2010
  • [Objective] To explore whether pollutants exposure has a measurable impact on urine 8-OH-dG level of healthy schoolchildren in traffic artery air polluted region.

    [Methods] A primary school near the trunk road with a distance about 30 meters was selected, from which 30 schoolchildren fit the qualifications were selected as the objects. The pollution le vels of SO2, NOX, O3 and PM2.5 were consecutively detected for five days in May and November, 2008 at the regional monitoring site in the playground. The pollution levels of SO2, NO2, O3 and PM10 were consecutively detected for 3 days in the same months at schoolchildren's activity places(classroom sites, extracurricular activity sites and sites on the way to school). Urine 8-OHdG content of the schoolchildren was also measured.

    [Results] The regional monitoring results showed that the pollution load coefficient of PM2.5 were 0.33 and 0.27 in May and November respectively, of NOX were 0.31 and 0.26, the two pollutants formed the biggest pollution load coefficients. Compared to May, the value of urine 8-OH-dG of schoolchildren increased with statistically significant difference in November (P<0.001). Urine 8-OH-dG level positively correlated with personal exposure to environmental pollutants with statistically significant difference (P<0.001), in which PM10 showed the largest regression coefficient (βPM10=0.40, βNO2=0.38, βO3=0.36, βSO2=0.36).

    [Conclusion] Exposure to traffic artery air pollution may be the influencing factor affecting urine 8-OH-dG level in healthy schoolchildren.

  • Related Articles

    [1]LI Dandan, MENG Zhonghua, QU Yingli, LI Yuanyuan, ZHU Huijuan, LIU Zhong, ZHAO Feng. Mediating effect of oxidative stress on association between nicotine and unexplained recurrent spontaneous abortion[J]. Journal of Environmental and Occupational Medicine, 2022, 39(5): 512-518, 526. DOI: 10.11836/JEOM21446
    [2]SHI Jingang, HE Miao. Advances on association between indoor air pollution and 8-hydroxydeoxyguanosine in human urine[J]. Journal of Environmental and Occupational Medicine, 2022, 39(4): 465-469. DOI: 10.11836/JEOM21315
    [3]ZHANG Hongdan, XU Cheng, WANG Tong, ZHANG Juan, SONG Ninghui. Associations of urinary organophosphate metabolites with oxidative stress levels in physical examination population in two hospitals of Nanjing[J]. Journal of Environmental and Occupational Medicine, 2021, 38(10): 1106-1112. DOI: 10.13213/j.cnki.jeom.2021.21239
    [4]PAN Cheng-yu, LU Qi, YAO Qian, TIAN Ying, GAO Yu. Polybrominated diphenyl ethers exposure in late pregnancy and child growth at 8 years of age[J]. Journal of Environmental and Occupational Medicine, 2020, 37(11): 1042-1049. DOI: 10.13213/j.cnki.jeom.2020.20281
    [5]WANG Kun, WANG Tong, ZHOU Yan-hua, PU Yue-pu, ZHANG Juan. Distribution of S-phenylmercapturic acid and 8-hydroxy-2'-deoxyguanosine in urine of workers exposed to low-concentration benzene[J]. Journal of Environmental and Occupational Medicine, 2020, 37(5): 413-420. DOI: 10.13213/j.cnki.jeom.2020.19802
    [6]WANG Ai-hong, LI Xiao-hai, LENG Peng-bo, FANG Lan-yun, WANG Qun-li, GAO GuoSheng. Influencing factors of urinary 8-OHdG concentration in male workers exposed to low levels of benzene[J]. Journal of Environmental and Occupational Medicine, 2020, 37(3): 243-248. DOI: 10.13213/j.cnki.jeom.2020.19550
    [7]NIU Ying-ying, ZHANG Bin, FU Ye, LI Xue-jing, LIU Yan-li, YANG Jin. Interaction effects of alcohol drinking and polycyclic aromatic hydrocarbons exposure on peripheral blood OGG1 methylation in coke oven workers[J]. Journal of Environmental and Occupational Medicine, 2019, 36(3): 197-203. DOI: 10.13213/j.cnki.jeom.2019.18633
    [8]LIU Yan-li, ZHANG Hong-jie, ZHANG Hui-tao, NIU Ying-ying, FU Ye, YANG Jin. Role of aryl hydrocarbon receptor expression in oxidative DNA damage induced by polycyclic aromatic hydrocarbons in coke oven workers[J]. Journal of Environmental and Occupational Medicine, 2018, 35(5): 400-405. DOI: 10.13213/j.cnki.jeom.2018.17585
    [9]DING Ting-ting, WANG Qian, ZHENG Guo-ying, LIU Ying-li, YUAN Ju-xiang, SHEN Fu-hai, JIANG Shou-fang, FENG Fu-min, JIN Yu-lan, GUAN Wei-jun, TONG Jun-wang. Effects of Benzene on Blood System and DNA Oxidative Damage in Mice[J]. Journal of Environmental and Occupational Medicine, 2016, 33(6): 571-574. DOI: 10.13213/j.cnki.jeom.2016.15562
    [10]WANG Yan-hua, LI Hongli, XIE Qiu-yan, XING Jie, JI Qian-peng, MENG Tao, NIU Yong, DUAN Hua-wei. Urinary 8-OHdG Levels and Related Impact Factors in General Population[J]. Journal of Environmental and Occupational Medicine, 2016, 33(4): 334-339. DOI: 10.13213/j.cnki.jeom.2016.15606

Catalog

    Article views (2693) PDF downloads (442) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return