Objective To explore the effect of styrene on lipid metabolism in occupational exposed persons.
Methods Indices of lipid metabolism total cholesterol (CHO), triglyceride (TG), high density lipoprotein (HDL), and low density lipoprotein (LDL)were measured in 108 styrene exposed persons and 115 controls. The relevant factors such as personal exposure dose and length of service were monitored and recorded. Then the correlation of the exposue and effects was analysed.
Results The contents of CHO and LDL showed no significance in the two groups (P > 0.05).TG was higher in the exposed persons than the controls, while HDL was lower (P < 0.05). The abnormal rate of HDL was higher in exposed group than the controls (P < 0.05), but other indices of lipid metabolism showed no significant difference between the two groups (P > 0.05).
Conclusion Styrene may have some effects on lipid metabolism in exposed persons such as TG and HDL.