Research progress on acetamiprid toxicity and exposure
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Abstract
Acetamiprid, an important kind of neonicotinoid insecticide, is widely used in agriculture all over the world because of its high insecticidal efficacy and relative safety to beneficial insects and mammals. In recent years, the biological toxicity effects of acetamiprid, especially its neurotoxicity effect through nicotinic acetylcholine receptors (nAChRs), have attracted many researchers. Acetamiprid can remain in crops and then enter the body through food intake in daily life, and has been detected in various foods and human tissues. Japan has conducted studies on human exposure levels of acetamiprid, but China has few reports and calls for more studies on population exposure levels and adverse health effects. This paper reviewed the toxicity effects and exposure levels of acetamiprid in human population. It started with the physical and chemical properties and usage of acetamiprid, then emphasized on the toxicity effects of acetamiprid with detailed information about acute, chronic, and developmental neurotoxicity effects, and finally summarized acetamiprid residues in food and exposure levels in general and occupational populations, aiming to provide new ideas and insights for further research on the toxicity and exposure level of acetamiprid.
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