Advances on effects of mitochondrial dynamics imbalance induced by environmental toxicants on neurogenesis
-
Abstract
Neurogenesis continues throughout life. The dynamic balance between mitochondria fission and fusion regulates self-renewal and differentiation of neural stem cells (NSCs). Environmental toxicants have been suggested to be involved in neurological disorders by damaging mitochondria which are the target of environmental toxicants. This review summarized the molecular mechanism of mitochondrial dynamics, their role in the process of neurogenesis, and the effects of mitochondrial dynamics imbalance induced by environmental toxicants on neurogenesis.
-
-
DownLoad: