Roles and mechanisms of circular RNAs in lung diseases caused by environmental exposure

LUO Hangjun; BIAN Qian

doi:10.11836/JEOM22014

Volume 39 Issue 12

Feb. 2023

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Journal of Environmental and Occupational Medicine > 2022 > 39(12): 1430-1437. > DOI: 10.11836/JEOM22014

LUO Hangjun, BIAN Qian. Roles and mechanisms of circular RNAs in lung diseases caused by environmental exposure[J]. Journal of Environmental and Occupational Medicine, 2022, 39(12): 1430-1437. DOI: 10.11836/JEOM22014

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Roles and mechanisms of circular RNAs in lung diseases caused by environmental exposure

LUO Hangjun^1,,
BIAN Qian^{1, 2, ,}

1.
School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China
2.
Institute of Toxicology and Risk Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China

Funds: This study was funded.

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Corresponding author:
BIAN Qian, E-mail: bianqian@jscdc.cn
Received Date: January 10, 2022
Accepted Date: August 29, 2022
Available Online: February 14, 2023

Graphical Abstract

Abstract

Abstract

Environmental exposure is an important factor in the occurrence and development of various lung diseases. Circular RNAs (circRNAs) are a class of noncoding RNA molecules, which are widely expressed in eukaryotes, and have been proved to play an important role in the occurrence and progression of a variety of human diseases. Studies have shown that circRNAs are closely related to various lung diseases, and have been used as diagnostic and prognostic biomarkers and therapeutic targets of some lung diseases. This review briefly described the physiological functions and molecular mechanisms of circRNAs, and summarized the regulatory mechanisms of circRNAs in lung diseases caused by environmental exposure, in order to provide new ideas for the research and application in related fields in the future.
- circular RNAs,
- lung disease,
- environmental exposure,
- regulation,
- molecular mechanism

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References

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