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Volume 39 Issue 2
Feb.  2022
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LI Yuanyuan, PENG Xiaohong. Research progress on intestinal probiotics alleviating chronic heavy metal toxicity[J]. Journal of Environmental and Occupational Medicine, 2022, 39(2): 218-222. DOI: 10.11836/JEOM21296
Citation: LI Yuanyuan, PENG Xiaohong. Research progress on intestinal probiotics alleviating chronic heavy metal toxicity[J]. Journal of Environmental and Occupational Medicine, 2022, 39(2): 218-222. DOI: 10.11836/JEOM21296
shu

Research progress on intestinal probiotics alleviating chronic heavy metal toxicity

Funds: This study was funded.
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  • Corresponding author:

    PENG Xiaohong,Email:pxh815@163.com

  • Received Date: July 03, 2021
  • Accepted Date: November 11, 2021
  • Published Date: February 24, 2022
    Graphical Abstract
    • Abstract
  • Human activities, especially industrial production, have aggravated the pollution of heavy metals in the environment, and especially after disrupting the food chain, such pollution can cause varying degrees of heavy metal poisoning in human beings. Studies have shown that exposure to heavy metals tends to upset the balance of the flora and further aggravate organ toxicity. Intestinal probiotics represented by Lactobacillus can actively adsorb heavy metal ions, promote their excretion, and reduce their induced oxidative stress injury and inflammatory response. Focusing on the chronic toxicity induced by long-term low-dose exposure to heavy metals, this article reviewed current pollution status of several common heavy metals (lead, cadmium, and mercury), analyzed the interaction between heavy metals, intestinal flora, and probiotics, and summarized proposed mechanisms of probiotics in mitigating chronic heavy metal toxicity, aiming to provide new ideas for effective prevention and treatment of organ toxicity induced by heavy metals.

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    • References (48)
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