Abstract: Living environment has a profound impact on human health, including temperature, air pressure, air pollution, water pollution, and occupational pollution. Based on the analysis of influence of common environmental factors on human health parameters, this paper presented a brief introduction on application examples of current environmental health risk assessment, and proposed that long-term human health assessment system could provide data on real-time individual health effects for environmental health risk assessment. By summarizing research status of long-term and long-distance multi-parameter health assessment system, this paper prospected its trend in order to provide a scientific basis for assessing the health impact of environment.