Abstract:
Benzo
apyrene (B
aP) is one of the most important occupational and environmental contaminants. Compared with its carcinogenicity and teratogenicity, its toxicity on neurodevelopment is a weak effect, but could cause serious and adverse consequences for the developing individuals, especially for the central nervous system, which is a very sensitive target. In this paper, based on the research progresses of B
aP toxicity on neurodevelopment at home and abroad, we summarized the epidemiological studies, neurotoxicity in animal models, and plausible mechanism due to B
aP exposure. Combined with our previous study, more attention should be paid to the damage to learning and memory by B
aP exposure.