镍化合物细胞损伤中自由基、ATP及Ca<sup>2+</sup>变化的研究进展

镍化合物细胞损伤中自由基、ATP及Ca²⁺变化的研究进展

详细信息

1.
Immunology Institutes, School of Basic Medicine of Lanzhou University, Lanzhou, Gansu 730000, China
2. Key Laboratory of Preclinical Study of New Drug of Gansu Province, Lanzhou University, Lanzhou, Gansu 730000, China

摘要

摘要: 镍化合物(nickel compounds)是人类在生产和生活中广泛接触的工业物质。镍化合物对细胞的损伤表现主要是以细胞自由基、磷酸三腺苷(ATP)和钙离子(Ca²⁺)及相关酶类和相关基因的变化。为进一步了解镍化合物对细胞自由基、ATP和Ca²⁺变化的影响,本文综述报道国内外对镍化合物细胞损伤中自由基、ATP和Ca²⁺方面变化的研究进展。
- 镍化合物 /
- 活性氧自由基 /
- 活性氮自由基 /
- 脂质过氧化 /
- 磷酸三腺苷 /
- 钙离子
Abstract: Nickle compounds are industrial materials with widely contact to human living and production. Nickle compounds mainly injury the cell in free radical, ATP and Ca²⁺ and genes associated with related enzyme changes. For research cell damaged by the nickel compounds, a review on free radical, ATP and Ca²⁺ in cell damaged by nickel compounds is presented.
- nickel compounds /
- reactive oxygen species /
- reactive nitrogen species /
- lipid peroxidation /
- adenosinetriphosphate(ATP) /
- Ca²⁺