微小RNA与肺癌关系的研究进展
Progress of the Studies on Relationship between MicroRNAs and Lung Cancer
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摘要:
微小 RNA(miRNAs)是近年来发现的一类转录后调控 mRNA翻译的非编码 RNA, 在生物的整个生命过程中发挥着重要作用。本文综述报道 miRNAs的生物合成和调控, miRNAs在肺癌发生中的作用机制以及 miRNAs与肺癌临床应用的研究进展。 Abstract: MicroRNAs(miRNAs)are endogenous non-coding RNAs,which regulate gene expression by post-transcriptional gene silencing. miRNAs have been implicated to play important roles in some biological processes,for example,the occurrence and development of lung cancer. This article mainly reviews the new discoreries in the relationship between miRNAs and lung cancer.
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