Abstract:
Objective To study the effect of 900 MHz electromagnetic radiation on circadian rhythm of spontaneous activity in mice.
Methods The 24-hour spontaneous activities of 30 mice were measured, and the circadian rhythms of spontaneous activity were fitted to cosine curve. Eighteen mice with obvious circadian rhythm were randomly divided into three groups:control group, radiation group A and radiation group B. Mice in radiation group A and radiation group B were exposed to 40 μW/cm2 900 MHz electromagnetic radiation at circadian time (CT) 0 or 12 respectively. The data obtained from different groups were analyzed with cosine model and compared with each other.
Results The parameters of cosine analysis showed statistical differences in median, amplitude and radian frequency between control group and group A, but, no obvious difference was observed between control group and group B.
Conclusion The circadian rhythm of spontaneous activity in mice could be influenced by 40μW/cm2 900 MHz electromagnetic radiation at CT0, but not at CT12.