Abstract: Bisphenol A (BPA), an endocrine disruptor, is commonly used in the production of polycarbonate (PC) and epoxy resin (ER). Both PC and ER are widely used in the manufacturing of various household supplies, such as PC bottles and inside/outside coating of food cans. BPA could migrate into foods or drinks in daily usage and enter human body to manifest adverse health effects. The present paper reviewed recent studies on the impact of internal and external BPA exposures on human health. Some critical issues and prospects were also proposed.