Abstract:
Objective To describe the clinical features and survival time of pulmonary cancer in female patients diagnosed and treated in a specialized hospital in Shanghai.
Methods To excerpt the chart of 346 female lung cancer patients diagnosed and treated in Shanghai Chest Hospital in the period from January 2000 to December 2001, and describe the clinical characteristics and major risk factors. Analysis and correlate the pathologic types and tumor stage with patients survival period through case followup.
Results The overall median age was 59 years. 19 cases (5.5%)were smokers and 34 cases (9.8%) had other respiratory diseases. 253 cases (80.8%)were adenocarcinoma, which was the highest proportion over all the other pathologic types. The second and third proportion was adeno-squamous carcinoma and squamous epithelial carcinoma. 65% of the cases were stage Ⅲ and stage IV when diagnosed; 110 cases received surgery, 5 cases received surgery combined with chemo-radiotherapy, 76 cases received surgery combined with chemotherapy, 29 cases received chemoradiotherapy, 34 cases did not receive any special treatment. The median survival times in patients of stage Ⅰa、Ⅰb、Ⅱa、Ⅱb、Ⅲa、Ⅲb、Ⅳ were 9.0、9.0、9.0、2.2、1.9、1.2、0.9 years respectively, The median survival times in patients with squamous carcinoma, adenocarcinoma, adeno-squamous carcinoma, SCLC were 7.0、2.0、1.7、1.2 years respectively, they were statistically significant in difference. The median survival times in patients who received surgery alone, surgery combined with chemoradiotherapy, surgery combined with chemotherapy, chemotherapy alone, chemoradiotherapy, and with out any special treatment were 8.3、6.3、2.9、1.0、0.9、0.7 years, respectively.
Conclusion Adenocarcinoma is the most common pathological types in female lung cancer in Shanghai. The pathologic types, tumor stage, and methods of treatments are the main prognostic factors for the overall survival in female lung cancer. It is necessary to strengthen people's awareness of and push forward the periodic physical examination. It is the most reliable means to detect and early diagnosis patient from high risk group, raise the accuracy of histopathological diagnosis, catch time for receiving surgical treatment, extend survival time, and improve the prognosis.
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