Abstract:
Objective To explore the curative effect of active carbon combined with nutritional intervention against lead poisoning in children.
Methods A total of 77 lead poisoning children visiting the selected outpatient department in a hospital, whose blood lead le vels were in the range of 100-249 μg/L and who did not receive lead expelling drugs, were randomly divided into a combined treatment group (n=39) and a traditional treatment group (n=38). The traditional treatment group was given routine nutritional in tervention (calcium 250 mg/d, zinc 10 mg/d, vitamin C 200 mg/d, and vitamin B1 5 mg/d, oral administration once daily at bedtime); the combined treatment group was additionally given activated carbon tablet 0.9 g/time before meal, 3 times/d. After continuous in tervention treatment for 30 d, the blood lead levels of the two groups were observed at the end of treatment and 30 d later.
Results At the end of treatment, the combined treatment group's average blood lead level dropped to normal range (98.13μg/L), low er than that of the traditional treatment group (118.10 μg/L) (P < 0.05). Twenty-five cases were cured with a cure rate of 64.1% in the combined treatment group, higher than that of the traditional treatment group (28.9%) (P < 0.01). On the 30th day after the treatment, the average blood lead level of the combined treatment group continued to drop to 68.75μg/L, while that of the traditional treatment group dropped to 108.77 μg/L with a decrease trend slowing down obviously; the cure rates of the two groups were 82.1% and 42.1%, respectively.
Conclusion Active carbon combined with nutritional intervention can significantly reduce blood lead level in children with le ad poisoning.
下载:
