男性钢铁工人倒班年限与高血压患病的关系:基于限制性立方样条模型

Relationship Between Shift Work Years and Hypertension in Male Steel Workers:Based on Restricted Cubic Spline Model

  • 摘要:
    目的 采用限制性立方样条模型探讨倒班年限与高血压的关系。
    方 法 2014年9月至2015年6月,对6 103名某钢铁企业男性工人进行面对面问卷调查。调查内容包括研究对象的一般情况和职业因素,同时测量血压。应用χ2检验和非条件logistic回归分析倒班与高血压的关系,采用限制性立方样条模型分析倒班年限与高血压的关系。
    结果 调整年龄、体质指数、文化程度、婚姻状况、家庭平均月收入、吸烟、饮酒、体育锻炼、嗜咸、父亲和母亲高血压患病及高温、噪声暴露情况后,曾经倒班和现在倒班者高血压的患病风险均为从不倒班者的1.255倍(95% CI分别为1.026~1.536,1.071~1.470)。限制性立方样条分析结果显示,倒班年限与高血压的关联强度有统计学意义(χ2=52.62,P<0.05),且呈非线性(χ2=13.05,P<0.05)。按开始倒班年龄分层后,<21岁和≥21岁者,倒班年限分别于23年和32年后高血压的患病风险呈下降趋势。
    结论 男性钢铁工人倒班年限与高血压患病有关。

     

    Abstract:
    Objective  To estimate the association of shift work years and hypertension based on restricted cubic spline model.
    Method  A total of 6 013 male workers from a steel enterprise were investigated by face to face interview from September 2014 to June 2015, including basic information and occupational factors. Measurement of blood pressure was conducted at the same time. Chi-square test and non-conditional logistic regression model were used to assess the relationship between shift work and hypertension. Restricted cubic spline model was used to estimate the relationship between shift work years and hypertension.
    Result  After adjusting age, body mass index (BMI), educational level, marital status, average family monthly income, smoking, drinking, physical activity, salt intake, parental/maternal hypertension, and high temperature and noise exposure, the prevalence rate of hypertension in the workers with current or former shift work was 1.255 times of those with never work (95%CI:1.026-1.536, 1.071-1.470). The results of restricted cubic spline model analysis showed a relationship with non-linearity (χ2=13.05, P<0.05) between shift work years and hypertension (χ2=52.62, P<0.05). After stratified by the age of first shift work, less-than-21-years-old was associated with decreased hypertension prevalence after 23 years of shift work, and equal-or-greater-than-21-years-old was associated with decreased hypertension prevalence after 32 years of shift work.
    Conclusion  A relationship is identified between shift work years and hypertension in male steel workers.

     

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