大气可吸入颗粒物对心血管疾病急救人次的短期影响

Short-Term Effect of Inhalable Particulate Matters on Emergency Ambulance Dispatches for Cardiovascular Diseases

  • 摘要:
    目的 探讨大气可吸入颗粒物(PM10)对心血管疾病急救人次的短期影响及其季节性差异。
    方法 收集2011—2014年宁波市急救中心的逐日心血管疾病急救数据,采用分布滞后非线性模型时间序列分析方法,在控制气象因素、长期趋势、星期几效应等混杂因素后,定量分析冷季(11月—次年4月)和暖季(5—10月)时PM10日均浓度与心血管病日急救人次的关系,并比较了PM10对不同人群组影响的差异。
    结果 研究期间共收集到心血管疾病急救病例7434例,其中冷季4123例,暖季3311例。暖季时,大气PM10每升高10 μg/m3,心血管疾病急救人次增加2.00%(95%CI:0.59%~3.42%),且未见滞后效应存在;全年和冷季时未见PM10对心血管疾病急救人次的影响有统计学意义。暖季时,PM10每升高10 μg/m3可造成男性和≥65岁年龄组人群心血管疾病急救人次分别增加2.41%(95%CI:0.48%~4.37%)和1.86%(95%CI:0.07%~3.69%);未见PM10对女性和 < 65岁年龄组人群的影响有统计学意义。
    结论 暖季时大气PM10浓度升高可造成心血管疾病急救人次增加,男性和老年人是敏感人群。

     

    Abstract:
    Objective To assess the short-term effect of particulate matters with an aerodynamic diameter less than 10 μm (PM10) on emergency ambulance dispatches for cardiovascular diseases (CVDs) and seasonal variations.
    Methods The data of daily emergency ambulance dispatches from 2011 to 2014 were collected from Ningbo Emergency Medical Center. A timeseries study using a distributed lag non-linear model was conducted to evaluate the relationship between PM10 and daily emergency ambulance dispatches for CVDs in cold season (from November to April) and warm season (from May to October) after controlling meteorological factors, long-term trend, and day of the week. We also examined the association stratified by sex and age.
    Results During the study period, a total of 7 434 cases of CVDs were collected, including 4 123 cases in cold season and 3 311 cases in warm season. In warm season, a 10-μg/m3 increase of PM10 was associated with 2.00% (95%CI: 0.59%-3.42%) increase in emergency ambulance dispatches for CVDs without lag effect identified. No effect was found in full year and cold season. In warm season, the excess risks associated with a 10-μg/m3 increase of PM10 in the males and the≥65 years old age group were 2.41% (95%CI: 0.48%-4.37%) and 1.86% (95%CI: 0.07%-3.69%) respectively. No statistically significant differences were found in the females and those less than 65 years old.
    Conclusion These findings suggest that the increase of PM10 are positively associated with the increase of emergency ambulance dispatches for CVDs in warm season; male and the senior may be more sensitive than others.

     

/

返回文章
返回