某家具生产基地甲醛-苯污染与胎儿畸形的相关性
Correlation between Fetal Malformation and Formaldehyde-Benzene Pollution in a Furniture Production Base
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摘要:
目的 探讨某家具生产基地甲醛-苯联合污染与胎儿畸形的相关性,为降低胎儿出生缺陷提供依据。 方法 以2010 年4 月-2012 年12 月佛山市顺德区龙江医院分娩及经产前诊断有胎儿畸形的80 例孕产妇,对其居住、工作环境进行甲醛、苯、甲苯、二甲苯浓度监测,并以同期正常儿的80 例孕产妇的情况进行对比分析。 结果 胎儿畸形中排行前4位依次为:先天性心脏病15例(占18.75%)、耳畸形13例(占16.25%)、脑畸形13例(占16.25%)、足内外翻7例(占8.75%)。畸胎组孕产妇居住或工作环境甲醛、苯、甲苯、二甲苯的浓度分别为(1.15& #177;0.35)、(0.44& #177;0.18)、(1.28& #177;0.35)、(2.18& #177;0.34)mg/m3,均明显高于对照组(P < 0.01);检测点超标率为96.25%~98.33%,明显高于正常组(P < 0.01)。 结论 胎儿畸形可能与甲醛-苯污染相关。 Abstract:Objective To explore the correlation of formaldehyde and benzene combined pollution with fetal malformation in a furniture production base, and to provide basis for birth defects reduction. Methods In Shunde Longjiang Hospital of Foshan city from April 2010 to December 2012, eighty pregnant women who gave birth to children with fetal malformations and whose fetus prenatally diagnosed to have malformations were enrolled in the study. Formaldehyde, benzene, toluene, and xylene concentrations in their living and working environment were measured and compared with those of mothers who delivered healthy children in the same period. Results The leading 4 fetal malformations in the participants were congenital heart disease (15 cases, 18.75%), ear malformation (13 cases, 16.25%), brain malformation (13 cases, 16.25%), and strephenopodia (7 cases, 8.75%). The air average concentrations of formaldehyde, benzene, toluene, and xylene exposed by the fetal malformation group were (1.15& #177;0.35), (0.44& #177;0.18), (1.28& #177;0.35), and (2.18& #177;0.34) mg/m3, respectively, significantly higher than those of the healthy group (P < 0.01). The disqualified air sample rates of the 4 selected chemicals ranged from 96.25% to 98.33%, which exceeded the corresponding national standards, and were significantly higher than those of the healthy group (P < 0.01). Conclusion Formaldehyde and benzene pollution are associated with fetal malformation.
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