上海市宝山区肺癌危险因素的病例对照研究
A Case-control Study on the Risk Factors of Lung Cancer in Baoshan District of Shanghai
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摘要:
目的 探讨室内装修及其他生活危险因素与肺癌的关系。 方法 采用1:1配对的病例对照研究方法,以2007年确诊的163例肺癌患者为病例组,选择在年龄、性别、住址方面相匹配的非肿瘤患者为对照组,进行条件Logistic回归分析。 结果 多因素分析结果存在统计学意义的因素包括肿瘤家族史(OR=4.090,P=0.001)、被动吸烟(OR=2.528,P=0.009)、住房10年内有过装修(OR=2.074,P=0.039)、室内经常通风(OR=0.160,P=0.028)、室内种植绿色植物(OR=0.483,P=0.027)和使用实木地板(OR=0.487,P=0.045)。 结论 有肿瘤家族史、被动吸烟和曾室内装修是肺癌的危险因素,室内经常通风、种植绿色植物、使用实木地板是肺癌的保护性因素。 Abstract:Objective To study whether the indoor decoration and other factor in living is risk factor of lung cancer. Methods A matched case-control study was conducted in 163 pairs of lung cancer cases and control in Baoshan District, 2007. The odds ratio (OR)was analyzed and checked with conditional logistic regression analysis. Results The results showed that the important risk factors of lung cancer included:family history of cancer(OR=4.090, P=0.001), passive smoking (OR=2.528, P=0.009), house decoration in past 10 years (OR=2.074, P=0.039), sufficient indoor ventilation (OR=0.160, P=0.028), indoor green plantation (OR=0.483, P=0.027), better material and type of floor (OR=0.487, P=0.045). Conclusion Family cancer history, passive smoking and house decoration with faulty material were risk factors of lung cancer, while sufficient indoor ventilation, indoor green plantation were protective factors against lung cancer.
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