浦东新区224名学龄儿童血清中双酚A水平调查
Investigation of Serum Bisphenol A Levels in 224 Schoolchildren in Pudong New Area
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摘要:
目的 了解学龄儿童血清中双酚A(BPA)水平,为健康评估提供科学依据。
方法 从浦东辖区内26所九年制学校、5所十二年制学校中分别随机选择3所和1所学校,共224名一年级在校学生作为研究对象,采用酶水解-高效液相色谱法对血清BPA进行检测。
结果 学龄儿童血清BPA的检出率为33.03%,浓度范围为未检出~38.04 μg/L,中位数低于检出限(0.139 μg/L),
P 75为4.15 μg/L。BPA的浓度和检出率在不同性别、年龄、体质指数儿童之间的差异均无统计学意义(P >0.05)。结论 该区学龄儿童血清中存在一定程度的BPA污染,个别儿童血清中BPA水平较高,应引起足够的重视。
Abstract:Objective To measure schoolchildren's serum level of bisphenol A in Pudong New Area, and to provide scientific evidence for health assessment of bisphenol A.
Methods First-grade pupils (
n =224) were selected from three out of twenty-six nine-year-system schools and one out of five twelve-year-system schools in Pudong New Area. Bisphenol A levels in serum were determined by high-performance liquid chromatography after enzyme hydrolysis.Results The detection rate of bisphenol A was 33.03% in the enrolled pupils. The concentrations of bisphenol A ranged from non-detectable to 38.04 μg/L (median < 0.139 μg/L;
P 75=4.15 μg/L). There was no statistical difference in the concentration or detection rate of bisphenol A among different gender, body mass index, and age groups (P >0.05).Conclusion Bisphenol A is detected in the serum of selected schoolchildren, and several cases show relatively high values, which require more attention.