严玉洁, 张芬, 李为希, 周洁, 许慧琳, 方红. 上海市闵行区2002-2012年大肠癌发病趋势及特征分析[J]. 环境与职业医学, 2016, 33(6): 575-580. DOI: 10.13213/j.cnki.jeom.2016.15722
引用本文: 严玉洁, 张芬, 李为希, 周洁, 许慧琳, 方红. 上海市闵行区2002-2012年大肠癌发病趋势及特征分析[J]. 环境与职业医学, 2016, 33(6): 575-580. DOI: 10.13213/j.cnki.jeom.2016.15722
YAN Yu-jie, ZHANG Fen, LI Wei-xi, ZHOU Jie, XU Hui-lin, FANG Hong. Temporal Trend and Features of Colorectal Cancer Incidence in Minhang District of Shanghai, 2002-2012[J]. Journal of Environmental and Occupational Medicine, 2016, 33(6): 575-580. DOI: 10.13213/j.cnki.jeom.2016.15722
Citation: YAN Yu-jie, ZHANG Fen, LI Wei-xi, ZHOU Jie, XU Hui-lin, FANG Hong. Temporal Trend and Features of Colorectal Cancer Incidence in Minhang District of Shanghai, 2002-2012[J]. Journal of Environmental and Occupational Medicine, 2016, 33(6): 575-580. DOI: 10.13213/j.cnki.jeom.2016.15722

上海市闵行区2002-2012年大肠癌发病趋势及特征分析

Temporal Trend and Features of Colorectal Cancer Incidence in Minhang District of Shanghai, 2002-2012

  • 摘要: 目的

    描述和分析上海市闵行区大肠癌发病趋势和特征,为进一步开展相关研究和完善相关防治策略提供依据。

    方法

    上海市闵行区2002年至2012年大肠癌年度发病数据来自上海市恶性肿瘤登记系统。采用世界标准人口计算标化发病率。趋势描述和分析采用美国国立癌症研究所(NCI)建立的平均年度变化百分比(average annualpercentage change)分析方法及Joinpoint软件(4.1.1.3版)。

    结果

    2002年至2012年间上海市闵行区居民男、女性和全人群大肠癌标化发病率变动均表现为上升趋势,平均每年分别上升2.44%(95% CI:1.61%~3.29%)、2.53%(95% CI:1.26%~3.82%)和2.43%(95% CI:1.91%~2.95%)。各人群的结肠癌和直肠癌标化发病率均呈上升趋势。大肠癌男女标化发病率比大于1,结肠癌和直肠癌标化发病率比大于1。闵行区分性别各年龄组人群中45至64岁组男、女性和全人群的大肠癌、结肠癌和直肠癌发病率表现出上升趋势,65岁及以上组男、女性和全人群大肠癌和结肠癌发病率均表现出上升趋势,65岁以上组人群直肠癌发病率未发现明显变化趋势。2002年至2012年间仅女性直肠癌占大肠癌发病构成表现出下降趋势,AAPC为-2.59(95% CI:-4.22~-0.94),其余部位发病构成变化无趋势性。

    结论

    除老龄直肠癌外,闵行区过去10年间各人群大肠癌发病风险呈上升趋势,女性直肠癌对发病风险的贡献下降。

     

    Abstract: Objective

    To describe the temporal trend and features of colorectal cancer (CRC) incidence in Minhang District of Shanghai, and to provide evidence for conducting further studies and refining relevant prevention strategies.

    Methods

    Annual incidence data of CRC in Minhang District during 2002-2012 were provided by the Shanghai Cancer Registry. Age standardized incidence rate (ASIR) was calculated based on the world standard population. Average annual percentage change (AAPC) and Joinpoint software (V4.1.1.3) from the National Cancer Institute (NCI) were used to describe the trend for CRC.

    Results

    During 2002-2012, the CRC ASIRs in Minhang District were ascending with a male AAPC of 2.44% (95%CI:1.61%-3.29%), a female AAPC of 2.53% (95%CI:1.26%-3.82%), and an overall AAPC of 2.43% (95%CI:1.91%-2.95%). The ASIRs for all sex-specific colon cancer and rectum cancer were also rising. The ratios of ASIRs for sex (male vs female) and site (colon vs rectum) were both more than 1. For the male, female, and both who were 45-64 years old, the incidence rates of CRC, colon cancer, and rectum cancer all showed ascending trends. For the three sex-specific groups who were 65 years and above, the incidence rates of CRC and colon cancer had ascending trends except rectum cancer. Among the sex-and site-specific proportions for CRC incidence, only the proportion of female rectum cancer incidents among all CRC incidents had a descending trend with an AAPC of-2.59 (95%CI:-4.22--0.94) during 2002-2012.

    Conclusion

    Except the rectum cancer for the elderly, the CRC incidence risks for different populations in Minhang District over past 10 years show rising trends. Female rectum cancer incidence contributes less over years to female CRC incidence.

     

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