上海某区足月新生儿低出生体重的影响因素分析
Influencing Factors of Full-Term Infants with Low Birth Weight in a District of Shanghai
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摘要:
目的 探讨孕期健康及行为相关因素对足月新生儿低出生体重的影响。 方法 采用队列研究,将上海某区孕期 < 20周的孕早期妇女纳入队列,最后分娩单胎足月活产儿的孕妇共2 768人。采用χ2检验和logistic回归分析孕期被动吸烟、文化程度、经济状况等因素和低出生体重的关系。 结果 在2 768名产妇中,有1 284人(46.4%)至少在孕早期或孕晚期有二手烟暴露的情况,孕妇低身高(模型1:OR=0.9,95% CI为0.840~0.996;模型2:OR=0.9,95%CI为0.860~0.998)及怀孕后患有疾病(模型1:OR=2.7,95% CI为1.1~6.5;模型2:OR=2.7,95% CI为1.1~6.6)会增加发生低出生体重儿的风险,孕早期或孕晚期的被动吸烟史对胎儿的出生体重没有影响。 结论 本研究并未发现孕期被动吸烟与胎儿低出生体重发生率之间的关联。 Abstract:Objective To evaluate the effect of health and behavior relevant influencing factors during pregnancy on newborn's weight. Methods Pregnant women from a district of Shanghai with less than 20 gestation weeks were enrolled in a cohort study.A total of 2 768 pregnant women gave birth to single live full-term neonates.The relationships between second-hand smoke (SHS) exposure,educational level,and economic status and low birth weight were analyzed by χ2 test and logistic regression model. Results Of the 2 768 pregnant women studied,1 284(46.4%) were exposed to SHS at least in the first or third trimester.Maternal short stature (Model 1:OR=0.9,95% CI 0.840-0.996;Model 2:OR=0.9,95% CI 00.860-0.998) and suffering from diseases during pregnancy (Model 1:OR=2.7,95% CI 01.1-6.5;Model 2:OR=2.7,95% CI 01.1-6.5) increased the risk of low birth weight.No significant difference was identified in newborn's low birth weight between maternal SHS exposure or not in the first or third trimester. Conclusion There is no evidence suggesting an association between mother's SHS exposure during pregnancy and newborn's low birth weightgroup
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