刘永, 梁佳, 郭家彬, 彭辉. 模式动物斑马鱼在微塑料毒性评价中的研究进展[J]. 环境与职业医学, 2022, 39(10): 1172-1179. DOI: 10.11836/JEOM22148
引用本文: 刘永, 梁佳, 郭家彬, 彭辉. 模式动物斑马鱼在微塑料毒性评价中的研究进展[J]. 环境与职业医学, 2022, 39(10): 1172-1179. DOI: 10.11836/JEOM22148
LIU Yong, LIANG Jia, GUO Jiabin, PENG Hui. Research progress of model animal zebrafish in toxicity evaluation of microplastics[J]. Journal of Environmental and Occupational Medicine, 2022, 39(10): 1172-1179. DOI: 10.11836/JEOM22148
Citation: LIU Yong, LIANG Jia, GUO Jiabin, PENG Hui. Research progress of model animal zebrafish in toxicity evaluation of microplastics[J]. Journal of Environmental and Occupational Medicine, 2022, 39(10): 1172-1179. DOI: 10.11836/JEOM22148

模式动物斑马鱼在微塑料毒性评价中的研究进展

Research progress of model animal zebrafish in toxicity evaluation of microplastics

  • 摘要:

    随着塑料产品的大量使用以及塑料垃圾的急剧增加,自然环境中降解产生以及工业人为添加的微塑料,已在食物、空气、海洋甚至极端地理环境中被检测出,作为新型污染物所带来的环境污染和机体健康损害已经成为亟待解决的全球科学问题。水生生物斑马鱼(Danio rerio)作为典型的模式动物,已被广泛应用在评价微塑料对机体健康评估研究中。本文综述了应用斑马鱼开展微塑料毒性评价的研究进展,重点介绍了微塑料对斑马鱼的毒性作用效应,简述了微塑料致斑马鱼毒性的影响因素,讨论了应用斑马鱼评价微塑料毒性研究的实验标准化问题,最后展望了未来研究方向。

     

    Abstract:

    With the extensive use of plastic products and the sharp increase of plastic waste, microplastics produced by degradation in the natural environment and artificially added by industry have been detected in food, air, ocean, and even extreme geographical environment. The environmental pollution and the biological health hazards caused by this new type of pollutant has become a global scientific problem to be solved urgently. Zebrafish (Danio rerio), as a typical model organism, has been widely used to evaluate the environmental pollution and health hazards caused by microplastics. This review on the research progress of model animal zebrafish in toxicity evaluation of microplastics mainly emphasized the toxic effects of microplastics on selected organs of zebrafish, briefly introduced the influencing factors of toxicity induced by microplastics, discussed the standardization of experiments for the evaluation of microplastic toxicity using zebrafish, and finally explored the future research directions.

     

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