DNA Oxidative Damage and Cancer

LI Xin-xin , YANG Gong-huan , SUN Xin . DNA Oxidative Damage and Cancer[J]. Journal of Environmental and Occupational Medicine, 2011, 28(5): 314-318.

Citation:

LI Xin-xin , YANG Gong-huan , SUN Xin . DNA Oxidative Damage and Cancer[J]. Journal of Environmental and Occupational Medicine, 2011, 28(5): 314-318.

Citation:

LI Xin-xin , YANG Gong-huan , SUN Xin . DNA Oxidative Damage and Cancer[J]. Journal of Environmental and Occupational Medicine, 2011, 28(5): 314-318.

Abstract

DNA damage induced by oxidative stress/lipid peroxidation may play an important role for driving normal cells to malignancy in the occurrence of human cancers. This review summarized the lipid peroxidation-induced DNA damage and its detection methods. DNA adducts could be applied as biomarkers of oxidative stress/lipid peroxidation in the study of the etiology and prevention of cancer.

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