Objective To describe the temporal trend and features of colorectal cancer (CRC) incidence in Minhang District of Shanghai, and to provide evidence for conducting further studies and refining relevant prevention strategies.
Methods Annual incidence data of CRC in Minhang District during 2002-2012 were provided by the Shanghai Cancer Registry. Age standardized incidence rate (ASIR) was calculated based on the world standard population. Average annual percentage change (AAPC) and Joinpoint software (V4.1.1.3) from the National Cancer Institute (NCI) were used to describe the trend for CRC.
Results During 2002-2012, the CRC ASIRs in Minhang District were ascending with a male AAPC of 2.44% (95%CI:1.61%-3.29%), a female AAPC of 2.53% (95%CI:1.26%-3.82%), and an overall AAPC of 2.43% (95%CI:1.91%-2.95%). The ASIRs for all sex-specific colon cancer and rectum cancer were also rising. The ratios of ASIRs for sex (male vs female) and site (colon vs rectum) were both more than 1. For the male, female, and both who were 45-64 years old, the incidence rates of CRC, colon cancer, and rectum cancer all showed ascending trends. For the three sex-specific groups who were 65 years and above, the incidence rates of CRC and colon cancer had ascending trends except rectum cancer. Among the sex-and site-specific proportions for CRC incidence, only the proportion of female rectum cancer incidents among all CRC incidents had a descending trend with an AAPC of-2.59 (95%CI:-4.22--0.94) during 2002-2012.
Conclusion Except the rectum cancer for the elderly, the CRC incidence risks for different populations in Minhang District over past 10 years show rising trends. Female rectum cancer incidence contributes less over years to female CRC incidence.
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