Research progress on epigenetic effects induced by perfluorooctane sulfonate

WENG Zhen-kun; GU Ai-hua

doi:10.13213/j.cnki.jeom.2018.17669

WENG Zhen-kun, GU Ai-hua. Research progress on epigenetic effects induced by perfluorooctane sulfonate[J]. Journal of Environmental and Occupational Medicine, 2018, 35(4): 371-376. DOI: 10.13213/j.cnki.jeom.2018.17669

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Research progress on epigenetic effects induced by perfluorooctane sulfonate

Abstract

Abstract

perfluorooctane sulfonate (PFOS) is widely used in food package, textile, paper, and insecticide. The toxic action of PFOS has attracted increasing attention due to its high persistence, bioaccumulation, potential carcinogenicity, and consequently great harm to ecological environment and human health. This review focused on the epigenetic effects of PFOS on DNA methylation, histone modification, and non-coding RNA regulation.

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