LU Yao, GAO Xue-juan, CONG Long-xue, MA Shi-tou, LIAO Ya-jing, MA Chong-qi, ZHANG Sheng-kui, XIAO Meng-ying, CHE Chong-liang, WANG Zhao-yang, YUAN Ju-xiang, HU Bo, LI Xiao-ming, FAN Hongmin. Effects of occupational high temperature exposure on renal function in male steel workers[J]. Journal of Environmental and Occupational Medicine, 2017, 34(10): 853-857. DOI: 10.13213/j.cnki.jeom.2017.17291
Citation: LU Yao, GAO Xue-juan, CONG Long-xue, MA Shi-tou, LIAO Ya-jing, MA Chong-qi, ZHANG Sheng-kui, XIAO Meng-ying, CHE Chong-liang, WANG Zhao-yang, YUAN Ju-xiang, HU Bo, LI Xiao-ming, FAN Hongmin. Effects of occupational high temperature exposure on renal function in male steel workers[J]. Journal of Environmental and Occupational Medicine, 2017, 34(10): 853-857. DOI: 10.13213/j.cnki.jeom.2017.17291

Effects of occupational high temperature exposure on renal function in male steel workers

  • Objective To assess the effects of occupational high temperature exposure on abnormal renal function in male steel workers, and to provide a theoretical basis for protection of rental function of this occupational group.

    Methods A total of 4 992 male steel workers from a steel group who received occupational health examination from October 2015 to May 2016 were selected as study subjects. A face-to-face questionnaire survey was conducted to collect demographic characteristics, lifestyle, and occupational high temperature exposure history. Blood samples were also collected to detect serum creatinine and calculate glomerular filtration rate adjusted by serum creatinine to estimate renal function. The effects of exposure to occupational high temperature and exposure years on abnormal renal function were analyzed by chi-square test, multiple logistic regression model, and restricted cubic spline model.

    Results A total of 4 400 workers were included in the analysis. After controlling age, educational level, per capita monthly in come, salt intake, smoking, alcohol consumption, and physical exercise, occupational high temperature exposure affected abnormal renal function in the male workers aged < 50 years (OR=1.85, 95%CI:1.16-2.95, P < 0.05). Restricted cubic spline model analysis results showed that high temperature exposure duration was associated with abnormal renal function (χ2=8.45, P < 0.05), showing a nonlinear dose-response relationship (χ2=5.44, P < 0.05). The risk of abnormal renal function increased gradually for < 20.5 years of occupational high temperature exposure, and decreased for >20.5 years.

    Conclusion Of the male steel workers aged < 50 years, occupational high temperature exposure may induce abnormal renal function, and there is a nonlinear dose-response relationship of high temperature exposure duration with abnormal renal function, showing a first-increasing-then-decreasing trend.

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