Progress on health effects of tungsten and its alloys
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Abstract
The main compositions of tungsten and its alloys include tungsten, cobalt, and tungsten carbide, which are the raw materials of hard alloys. This paper introduced the exposure levels and major health effects of tungsten and its alloys, and summarized research results on related dose-response relationship and genetic susceptibility. It could be concluded that there were relationships between external exposure dose and internal exposure dose (such as urine or blood sample) or between external exposure dose and selected biomarkers. Meanwhile, individual variance also played an important role in the health effects of tungsten and its alloys. It is urgent to conduct health impact assessment research on tungsten and its alloys in order to control a new statutory occupational disease, hard metal lung disease, in China.
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