Objective To establish a method for pentachlorophenol determination in human urine by headspace solid phase microextraction coupled with gas chromatography.
Methods Headspace solid phase microextraction technology was used to enrich pentachlorophenol in urine.The extraction conditions and the chromatographic column were optimized.Pentachlorophenol was determined with electron capture detector.
Results The linear dection rang for pentachlorophenol in urine was 0.50-5.00 mg/L;the correlation coefficient was 0.999 3;and the limit of detection was 0.09 mg/L.The average recovery rate for pentachlorophenol was from 97.6% to 103.7%,with relative standard deviations of 1.63%-6.78%.
Conclusion The method is featured by easy sample preparation,low limit of detection,and high accuracy,and suitable for the determination of pentachlorophenol in worker's urine.
DownLoad: