环氧树脂厂工人双酚A接触水平调查
Exposure Levels of Bisphenol A among Workers in A Resin Factory
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摘要:
目的 评估树脂厂工人双酚 A接触水平, 为下一步建立剂量反应关系作基础。 方法 2010年选择某树脂厂, 在对现场生产工艺流程、设备等的调查基础上, 进行定点及个体空气采样, 并收集 154名工人班前尿及班后尿,酶解检测总双酚 A水平; 另收集当地无明确双酚 A源水厂的 109名工人尿样作为生物监测的对照组。 结果 树脂厂96.5%的空气样品测出双酚 A。树脂厂工人班前尿与班后尿肌酐校正总双酚 A水平中位数分别为 11.31、16.17 μg/g, 班后尿水平高于班前尿水平(P < 0.05)。对照组肌酐校正水平中位数分别为 2.96、2.56 μg/g, 明显低于树脂厂工人的检测值(P <0.001), 其单侧 95%上限分别为 19.05、28.84μg/g。 结论 树脂厂工人双酚 A接触水平高, 有必要采取措施控制接触水平。 Abstract:Objective To assess bisphenol A (BPA) exposure levels of workers and to provide basis for studying its doseresponse correlation. Methods In 2010, local and personal airborne samples were taken in a resin factory. Spot urine samples of 154 workers from the resin factory and 109 workers from a control factory were collected before and after shifts to measure total BPA. Results In the resin factory, 96.5% of the air samples were BPA detectable; the medians of creatinine-adjusted urinary BPA levels pre-and post-shift were 11.31 and 16.17 μg/g respectively, and the urinary BAP levels of post-shift was significantly higher than that of pre-shift (P < 0.05). In the control factory, the medians of creatinine-adjusted urinary BPA levels were 2.96 and 2.56μg/g respectively, which was significantly lower than those in the resin factory (P < 0.001), and one-side 95% upper bounds were 19.05 and 28.84 μg/g, respectively. Conclusion Workers from the resin factory are occupationally exposed to BPA at a high level. It is necessary to control the occupational exposure level of BPA.
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