长期辐射对男性放射工作人员外周血T、B、NK淋巴细胞的影响
Effects of Long-term Ionizing Radiation on T,B and NK Lymphocyte Subsets in Peripheral Blood of Male Roentgenogramphy Workers
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摘要:
目的 探讨长期辐射对男性放射人员T、B、NK淋巴细胞亚群水平的影响。 方法 检测32名男性放射工作人员T、B、NK细胞中各亚群在淋巴细胞中的百分率,按受照辐射总剂量进行分组比较。 结果 CD3+CD8+T在 ≤ 20 mSv和>20 mSv组间的百分比分别为(24.91& #177;7.21)%和(18.68& #177;6.99)%,差异具有统计学意义(t=2.430,P<0.05), CD8+CD45RO+T在 ≤ 20 mSv和>20 mSv组间的百分比分别为(6.54& #177;2.65)%和(4.15& #177;1.93)%,差异具有统计学意义(t=2.780, P<0.01)。 结论 长期电离辐射能引起CD3+CD8+T和CD8+CD45RO+T的降低,应加强监控。 Abstract:Objective To investigate the effects of long-term ionizing radiation on T,B and NK lymphocyte subsets in peripheral blood of male roentgenography workers. Methods The T,B and NK lymphocyte subsets in the peripheral blood lymphocyte of 32 male roentgenography workers were examined and compared among stratified groups with gradient radiation dose. Results There were significant difference (t=2.430,P<0.05) between the percents of CD3+CD8+T cells in lymphocyte of ≤ 20 mSv group(24.91& #177;7.21)%versus >20 mSv group(18.68& #177;6.99)%.The percents of CD8+CD45RO+T cells in lymphocyte between ≤ 20 mSv group(6.54& #177;2.65)%versus>20 mSv group(4.15& #177;1.93)% were significantly different also (t=2.780,P<0.01). Conclusion Reduction of CD3+CD8+T and CD8+CD45RO+T subsets of lymphocyte may be resulted in long-term ionizing radiation in male roentgenography workers.Attention in monitoring on these changes should be enforced.
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