某高校3 635例教职工高尿酸血症患病情况及相关因素分析
Prevalence and Correlated Factors of Hyperuricaemia in 3 635 Persons among University Staff
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摘要:
目的 了解高校教职工高尿酸血症患病情况,以及高尿酸血症与质量指数(BMI)、腰围、血压、血脂、血糖的关系,为针对性的健康教育提供依据。 方法 对某高校3 635名教职工进行健康体检。内容:问卷调查、查体和实验室检查。问卷调查包括:一般情况、既往病史及吸烟、饮酒、锻炼等情况。查体包括:身高、体重、腰围和血压等。实验室检查有:空腹血糖(FBG)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、肌酐(Cr)和血尿酸等。 结果 参加体检的3 635名教职工中,血尿酸水平增高者740人(占20.36%),男性检出率明显高于女性,差异有统计学意义(P<0.05)。高尿酸血症的发生率随年龄的增长而增加。高尿酸血症组的血压、TG、TC、LDL-C)、BMI、腰围、FBG明显高于尿酸正常组,差异有统计学意义(P<0.005)。Logistic回归分析结果显示:男性、超重或肥胖、有高血压病史、TG高、TC高、HDL-C低及Cr升高为高尿酸血症的危险因素(OR分别为1.295、2.607、1.314、1.425、1.461、1.396、2.543)。 结论 该校教职工高尿酸血症检出率较高,提示高校医院应加强高尿酸血症的防治。 Abstract:Objective To study the prevalence of hyperuricemia, and its related factors in a university staff. The research may provide some valuable reference for the health education in universities. Methods Physical examinations were performed on 3 635 persons in the staff of a university in Beijing. The contents included questionnaire survey:general condition, past medical history, smoking, and drinking; physical examination:height, body mass, waist circumference, and blood pressure etc.; and laboratory examinations:fasting blood glucose (FBG), total cholestero(l TC), triglyceride (TG), high density lipoprotein cholestero(l HDL-C), low density lipoprotein cholestero(l LDL-C), creatinine (Cr)and uric acid. Results The detection rate of hyperuricemia was 20.36%. The rate in males was significantly higher than that in females. The detection rate of hyperuricemia also increased with age. The abnormal rates of blood pressure, TG, TC, LDL-C, BMI, waist circumference, FBG in hyperuricemia group were significantly higher than those in the group with normal uric acid content. Logistic regression analysis showed that sex, BMI, hypertension history, TG, TC, HDL-C, and Cr were risk factors of hyperuricemia (OR:1.295, 2.607, 1.314, 1.425, 1.461, 1.396, and 2.543 respectively). Conclusion The prevalence of hyperuricemia among university staff was higher. Thus, attention should be paid to the early diagnosis and treatment of hyperuricemia in the staff of the university.
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