社会心理因素与乳腺癌的关联:一项病例-对照研究
Relationship Between Social Mental Factors and Breast Cancer: A Case-Control Study
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摘要:
目的 探讨社会心理因素与乳腺癌的关联，为乳腺癌患者的心理干预提供理论依据。
方法 通过自行设计的一般人口学问卷、匹兹堡睡眠质量指数量表、简明职业紧张问卷、特质应对方式量表和社会支持量表对134对按照1∶1配对原则的病例组和对照组研究对象进行流行病学调查。
结果 病例组匹兹堡睡眠质量指数量表的睡眠质量、入睡时间、睡眠障碍、日间功能障碍、总分和特质应对方式量表的消极应对得分高于对照组（
P <0.05）；病例组简明职业紧张问卷的社会支持，社会支持量表的主观支持、支持利用度和总分低于对照组（P <0.05），其他各维度和总分两组间得分差异无统计学意义（P >0.05）。非条件logistic回归分析显示，睡眠时间、社会支持、支持利用度为乳腺癌的保护因素（OR =0.547、0.495、0.697，95%CI 为0.310～0.967、0.245～0.997、0.591～0.821），睡眠障碍、积极应对、客观支持为乳腺癌的危险因素（OR =4.619、1.053、1.379，95%CI 为2.406～8.866、1.000～1.108、1.177～1.615）。结论 睡眠质量、职业紧张、应对方式和社会支持可能与乳腺癌发生相关。
Abstract:Objective To investigate social mental risk factors of breast cancer (BC) patients and provide a theoretical basis for their psychological intervention.
Methods With a 1:1 matched-pair case-control study design, a total of 134 BC patients and 134 healthy women were investigated by self-designed general demographic questionnaire, Pittsburgh Sleep Quality Index (PSQI) questionnaire, occupational stress questionnaire, coping style scale, and social support scale.
Results The scores of sleep quality, sleep time, sleep disorder, daytime dysfunction, PSQI, and negative coping in the BC patients were significant higher than those in the controls (
P <0.05); the scores of social support dimension, subjective support, support utilization, and social support scale total were lower (P <0.05); and the scores of other dimensions and relevant total were not statistically different (P >0.05). The results of unconditional logistic regression analysis showed that the protective factors of BC were sleep time, social support, and support utilization (OR =0.547, 0.495, and 0.697; 95%CI :0.310-0.967, 0.245-0.997, and 0.591-0.821) and risk factors were sleep disorders, positive coping, and objective support (OR =4.619, 1.053, and 1.379; 95%CI :2.406-8.866, 1.000-1.108, and 1.177-1.615).Conclusion Sleep quality, occupational stress, coping style, and social support could be associated with the incidence of breast cancer.
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