郑光, 田丽婷, 刘武忠, 过伟军, 金泰廙. 职业性铅接触工人血铅水平下降与神经传导速度变化的关系[J]. 环境与职业医学, 2015, 32(8): 739-743. DOI: 10.13213/j.cnki.jeom.2015.14540
引用本文: 郑光, 田丽婷, 刘武忠, 过伟军, 金泰廙. 职业性铅接触工人血铅水平下降与神经传导速度变化的关系[J]. 环境与职业医学, 2015, 32(8): 739-743. DOI: 10.13213/j.cnki.jeom.2015.14540
ZHENG Guang , TIAN Li-ting , LIU Wu-zhong , GUO Wei-jun , JIN Tai-yi . Relationship between Blood Lead Decrease and Nerve Conduction Velocity Change in Occupational Lead Exposed Workers[J]. Journal of Environmental and Occupational Medicine, 2015, 32(8): 739-743. DOI: 10.13213/j.cnki.jeom.2015.14540
Citation: ZHENG Guang , TIAN Li-ting , LIU Wu-zhong , GUO Wei-jun , JIN Tai-yi . Relationship between Blood Lead Decrease and Nerve Conduction Velocity Change in Occupational Lead Exposed Workers[J]. Journal of Environmental and Occupational Medicine, 2015, 32(8): 739-743. DOI: 10.13213/j.cnki.jeom.2015.14540

职业性铅接触工人血铅水平下降与神经传导速度变化的关系

Relationship between Blood Lead Decrease and Nerve Conduction Velocity Change in Occupational Lead Exposed Workers

  • 摘要: 目的 探讨职业性铅接触工人血铅水平降低和神经传导速度增高之间的相关关系。

    方法 分别于2007、2009年检测某电池厂空气铅浓度和60名职业铅接触工人与91名对照组工人的血铅值、运动神经及感觉神经传导速度,用协方差分析和相关分析对两者的变化关系进行探讨。

    结果 铅接触组2009年度血铅水平较2007年度血铅水平有明显降低,由2007年度的(657.9& #177;216.4)μg/L降至2009年度的(345.8& #177;169.2)μg/L,与年龄、性别无关; 2009年度感觉神经传导速度较2007年度有明显增加(P<0.05)。男性工人正中神经、尺神经、腓浅神经感觉传导速度增加值与血铅下降值之间存在一定的相关关系,相关系数分别为0.365、0.276、0.17,具有统计学意义。对照组2009年度神经传导速度较2007年度未见明显变化。

    结论 男性工人血铅下降水平和感觉神经传导速度增加值之间存在着一定的相关关系。可通过及时控制血铅水平,达到改善感觉神经传导速度的目的。

     

    Abstract: Objective To analyze the relationship between decreasing values of blood lead and the elevation of nerve conduction velocity in occupational lead exposure workers.

    Methods Blood lead levels and the conduction velocity of motion nerve and sense nerve of 60 occupational lead exposure workers and 91 controls were measured in 2007 and 2009. Co-variance and correlation analyses were applied to assess the relationship.

    Results The blood lead value in the lead exposure workers dropped remarkably from (657.9& #177;216.4)μg/L in 2007 to (345.8& #177;169.2)μg/L in 2009, and showed no age or gender differences. The sense nerve conduction velocity of the lead exposure workers also increased remarkably in 2009 than in 2007 (P<0.05). Lower blood lead levels were correlated with higher sense velocities of median nerve, ulnar nerve, and superficial peroneal nerve, and the correlation coefficients were 0.365, 0.276, and 0.17, respectively. The nerve conduction velocity of the control group had no remarkable change in 2009 as compared with 2007.

    Conclusion There is a correlation between the decreasing value of blood lead and the increasing value of sense velocity. Controlling the blood lead level in time could restore sense conduction velocity.

     

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