王帅, 董淑英, 孙阔, 孙卓茹, 曹佳. 哈尔滨市孕妇全血有机物鉴别及邻苯二甲酸酯类暴露水平分析[J]. 环境与职业医学, 2014, 31(3): 210-212,216. DOI: 10.13213/j.cnki.jeom.2014.0050
引用本文: 王帅, 董淑英, 孙阔, 孙卓茹, 曹佳. 哈尔滨市孕妇全血有机物鉴别及邻苯二甲酸酯类暴露水平分析[J]. 环境与职业医学, 2014, 31(3): 210-212,216. DOI: 10.13213/j.cnki.jeom.2014.0050
WANG Shuai , DONG Shu-ying , SUN Kuo , SUN Zhuo-ru , CAO Jia . Organic Matters Identifcation and Phthalates Levels in Whole Blood of Pregnant Women in Harbin[J]. Journal of Environmental and Occupational Medicine, 2014, 31(3): 210-212,216. DOI: 10.13213/j.cnki.jeom.2014.0050
Citation: WANG Shuai , DONG Shu-ying , SUN Kuo , SUN Zhuo-ru , CAO Jia . Organic Matters Identifcation and Phthalates Levels in Whole Blood of Pregnant Women in Harbin[J]. Journal of Environmental and Occupational Medicine, 2014, 31(3): 210-212,216. DOI: 10.13213/j.cnki.jeom.2014.0050

哈尔滨市孕妇全血有机物鉴别及邻苯二甲酸酯类暴露水平分析

Organic Matters Identifcation and Phthalates Levels in Whole Blood of Pregnant Women in Harbin

  • 摘要: 目的 了解哈尔滨地区孕妇血液中有机物成分及邻苯二甲酸酯类暴露水平。

    方法 随机选取哈尔滨市区和郊区健康的孕妇100名,分别采集全血2 mL,并收集调查问卷表,应用气相色谱-质谱联用技术对血液中有机物成分进行定性分析,并对邻苯二甲酸酯做定量分析。

    结果 孕妇全血样品中共检出有机物70种,其中邻苯二甲酸酯类4种,分别为邻苯二甲酸丁酯(DBP)、邻苯二甲酸(2-乙基)己酯(DEHP)、邻苯二甲酸二异丁酯(DIBP)、邻苯二甲酸二甲酯(DMP)。市区与郊区、20岁~、30岁~组孕妇血液中4种邻苯二甲酸酯含量差异均无统计学意义。常用塑料制品打包或加热食物组孕妇血液中DBP、DIBP含量明显高于不使用组(DBP,P=0.041;DIBP,P=0.004)。

    结论 哈尔滨市孕妇全血中检出多种环境有机污染物,使用塑料制品盛装或加热食物可导致孕妇血液中邻苯二甲酸酯类暴露。

     

    Abstract: Objective To examine the components of organic matters and the levels of phthalates (PAEs) exposure in the whole blood of pregnant women in Harbin.

    Methods Whole blood (2 mL) was sampled from each of 100 healthy pregnant women randomly selected from urban and suburban areas in Harbin.A face-to-face interview was conducted to collect information on general demographic characteristics and plastic exposure using questionnaires.Gas chromatography and mass spectrometry (GC/MS) was applied for qualitative analysis of organic components and quantitative analysis of phthalates.

    Results Seventy types of organic matters were detected in the pregnant women's whole blood samples,including four kinds of PAEs,i.e.dibutyl phthalate (DBP),di-2-ethylhexyl phthalate (DEHP),diisobutyl phthalate (DIBP),and dimethyl phthalate (DMP).There were no statistical differences in the four phthalates concentrations between the urban and the suburban areas (P > 0.05),nor between the 20's and the 30's age groups (P >0.05).The concentrations of DBP and DIBP in those who often used and heated plastic food containers were higher than those did not (DBP,P=0.041;DIBP,P=0.004).

    Conclusion The pregnant women's whole blood contain various types of environmental organic pollutants.The usage of plastic products for heating or packing food may elevate exposure to DBP and DIBP in pregnant women's blood.

     

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