GU Yi-qin, CHEN Ren-jie, CHEN Li, YING Sheng-jie. Associations between ambient air pollution and preterm birth in Minhang District, Shanghai[J]. Journal of Environmental and Occupational Medicine, 2019, 36(2): 106-111. DOI: 10.13213/j.cnki.jeom.2019.18776
Citation: GU Yi-qin, CHEN Ren-jie, CHEN Li, YING Sheng-jie. Associations between ambient air pollution and preterm birth in Minhang District, Shanghai[J]. Journal of Environmental and Occupational Medicine, 2019, 36(2): 106-111. DOI: 10.13213/j.cnki.jeom.2019.18776

Associations between ambient air pollution and preterm birth in Minhang District, Shanghai

  • Objective Maternal exposure to air pollution during pregnancy has been linked to adverse birth outcomes. This study aims to explore the associations between ambient air pollution and preterm birth in Minhang District, Shanghai and the potential effect modifiers.

    Methods We collected data about all newborns delivered in 2015 and 2016 and their mothers in Minhang District, as well as air pollution and weather conditions in the same area and same years. In this case-control study, unconditional logistic regression models were established to analyze the associations between different ambient air pollutants and preterm birth. Stratification analyses were conducted to explore the potentially different impacts of air pollution in relation to individual characteristics.

    Results During the study period, 6 hospitals in Minhang District recorded 29 324 live births, of which there were 1 402 preterm births (4.8%). The annual average levels of PM2.5 (50.4 μg/m3) and NO2 (44.3 μg/m3) exceeded the National Air Quality Standard. In the first trimester, various air pollutants showed no significant impacts on preterm births. In the second trimester, PM2.5 and CO showed significant effects with 11.2% (95% CI:6.7%-15.6%) and 15.6% (95% CI:12.0%-19.1%) increments of preterm births respectively in association with an interquartile range increase in their concentrations (PM2.5:20.8 μg/m3, CO:0.2 mg/m3). In the third trimester, all air pollutants were significantly associated with increased preterm births; an interquartile range increase in the concentrations of PM2.5 (20.3 μg/m3), SO2 (7.2 μg/m3), NO2 (17.2 μg/m3), CO (43.7 μg/m3), and O3 (0.2 mg/m3) corresponded to increments of 14.6% (95% CI:3.3%-25.8%), 6.3% (95% CI:2.3%-10.3%), 13.8% (95% CI:5.8%-21.7%), 29.8% (95% CI:21.9%-37.8%), and 9.5% (95% CI:2.4%-16.6%) in preterm birth, respectively. The results of stratification analyses showed exposure to air pollutants during the second and third trimesters would lead to higher risks of preterm births for female fetus, multiple birth, and pregnant women with second or more deliveries and older than 35 years.

    Conclusion Maternal exposure to air pollution in the second and third trimesters would increase the risk of preterm birth in Minhang District of Shanghai.

  • loading

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return