Persistent organic pollutants (POPs) are a sort of substances with high toxicity, biological accumulation, lipophilicity, and semivolatility.A large number of studies have shown that POPs can result in adverse health effects, and the mechanisms are not clear yet.This paper introduced the toxic effects and related mechanisms of such typical POPs as polychlorinated dibenzo-p-dioxins and dibenzofurans and polychlorinated biphenyls on nervous, reproductive, endocrine, and other systems or organs, aiming to provide a theoretical basis for further mechanism research.
KATSOYIANNIS A, CINCINELLI A.On persistent organic pollutants in Italy-From Seveso to the Stockholm Convention and beyond[J].Sci Total Environ, 2017, 579:514-516.
RÍOS J M, LANA N B, CIOCCO N F, et al.Implications of biological factors on accumulation of persistent organic pollutants in Antarctic notothenioid fish[J].Ecotoxicol Environ Saf, 2017, 145:630-639.
BERGHUIS S A, BOS A F, SAUER P J, et al.Developmental neurotoxicity of persistent organic pollutants:an update on childhood outcome[J].Arch Toxicol, 2015, 89(5):687-709.
WINNEKE G.Developmental aspects of environmental neurotoxicology:lessons from lead and polychlorinated biphenyls[J].JNeurol Sci, 2011, 308(1/2):9-15.
NISHIJO M, TAI P T, ANH N T, et al.Urinary amino acid alterations in 3-year-old children with neurodevelopmental effects due to perinatal dioxin exposure in Vietnam:a nested case-control study for neurobiomarker discovery[J].PLoS One, 2015, 10(1):e0116778.
JOHANSSON N, FREDRIKSSON A, ERIKSSON P.Neonatal exposure to perfluorooctane sulfonate(PFOS)and perfluorooctanoic acid(PFOA)causes neurobehavioural defects in adult mice[J].NeuroToxicology, 2008, 29(1):160-169.
GUO XX, HE QZ, LI W, et al.Brain-derived neurotrophic factor mediated perfluorooctane sulfonate induced-neurotoxicity via epigenetics regulation in SK-N-SH Cells[J].Int J Mol Sci, 2017, 18(4):893.
ZHENG S, LIU C, HUANG Y, et al.Effects of 2, 2', 4, 4'-tetrabromodiphenyl ether on neurobehavior and memory change and bcl-2, c-fos, grin1b and lingo1b gene expression in male zebrafish (Danio rerio)[J].Toxicol Appl Pharmacol, 2017, 333:10-16.