LIU Wen-yuan, SHI Dan-hua, WU Jun-hu, XU Ya-nan, LU Wen-bo, QIU Hai-yan. A time-series analysis on association between exposure to six air pollutants and preterm birth in Ningbo[J]. Journal of Environmental and Occupational Medicine, 2018, 35(1): 19-23. DOI: 10.13213/j.cnki.jeom.2018.17500
Citation: LIU Wen-yuan, SHI Dan-hua, WU Jun-hu, XU Ya-nan, LU Wen-bo, QIU Hai-yan. A time-series analysis on association between exposure to six air pollutants and preterm birth in Ningbo[J]. Journal of Environmental and Occupational Medicine, 2018, 35(1): 19-23. DOI: 10.13213/j.cnki.jeom.2018.17500

A time-series analysis on association between exposure to six air pollutants and preterm birth in Ningbo

  • Objective To analyze the effects of exposure to six air pollutantsfine particulate matters (PM2.5), coarse particulate matters (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) on preterm birth in Ningbo.

    Methods A generalized linear distributed lag model for time-series data was adopted. The effects of the concentrations of six air pollutants on preterm birth from January 2014 to December 2015 in Ningbo were assessed after controlling confounding factors such as long-term trends, meteorological factors, and day of the week.

    Results Significant lag effects of PM2.5, SO2, NO2 (each 10 μg/m3 increase), and CO (each 0.1 mg/m3 increase) were identified on preterm birth, with RR (95%CI) of 1.015 (1.000-1.032) for PM2.5 on lag1; 1.073 (1.016-1.133), 1.053 (1.000-1.109), 1.060 (1.009-1.115), and 1.062 (1.010-1.116) for SO2 on lag0, lag2, lag3, and lag4; 1.031 (1.005-1.058) and 1.027 (1.002-1.054) for NO2 on lag0 and lag1; and 1.350 (1.079-1.688) for CO on lag3, respectively. Significant accumulative effects were only shown for SO2 on preterm birth, with RR (95%CI) of 1.099 (1.019-1.186) and 1.091 (1.001-1.189) for average 1 week and 2 weeks of accumulation.

    Conclusion Exposure to air pollutants may contribute to the risk of preterm birth, showing both lag effects and accumulative effects.

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