李文, 廖雪梅, 罗琳, 胡亚男. 2006—2019年重庆市渝北区尘肺病报告病例特征及生存分析[J]. 环境与职业医学, 2021, 38(8): 872-876. DOI: 10.13213/j.cnki.jeom.2021.21063
引用本文: 李文, 廖雪梅, 罗琳, 胡亚男. 2006—2019年重庆市渝北区尘肺病报告病例特征及生存分析[J]. 环境与职业医学, 2021, 38(8): 872-876. DOI: 10.13213/j.cnki.jeom.2021.21063
LI Wen, LIAO Xuemei, LUO Lin, HU Yanan. Incidence characteristics and survival analysis of reported pneumoconiosis in Yubei District of Chongqing from 2006 to 2019[J]. Journal of Environmental and Occupational Medicine, 2021, 38(8): 872-876. DOI: 10.13213/j.cnki.jeom.2021.21063
Citation: LI Wen, LIAO Xuemei, LUO Lin, HU Yanan. Incidence characteristics and survival analysis of reported pneumoconiosis in Yubei District of Chongqing from 2006 to 2019[J]. Journal of Environmental and Occupational Medicine, 2021, 38(8): 872-876. DOI: 10.13213/j.cnki.jeom.2021.21063

2006—2019年重庆市渝北区尘肺病报告病例特征及生存分析

Incidence characteristics and survival analysis of reported pneumoconiosis in Yubei District of Chongqing from 2006 to 2019

  • 摘要: 背景

    尘肺病是中国职业人群中最常见的、危害最严重的职业性疾病,发病情况仍十分严峻,目前生存分析相关报道较少。

    目的

    掌握重庆市渝北区尘肺病报告病例的发病特征及生存状况,为当地尘肺病防治对策提供依据和建议。

    方法

    通过职业病及健康危害因素监测信息系统、职业病诊断和鉴定机构、2020年职业性尘肺病随访调查项目收集2006—2019年重庆市渝北区新发尘肺病病及其生存资料。采用卡方检验或Fisher确切概率法比较矽肺和煤工尘肺在发病分期、诊断时间、接尘工龄等方面的差异,采用Kaplan-Meier法进行生存分析,生存曲线组间比较采用log-rank检验。

    结果

    2006—2019年渝北区共报告新发尘肺病768例,诊断年龄中位数M及第25、75百分位数(P25P75)为57(50,64)岁,男性为主(99.9%),煤工尘肺最多(54.0%)。新发矽肺壹期、贰期、叁期均在2012年出现发病高峰,新发煤工尘肺壹期2015年出现发病高峰,2016—2019年新发尘肺病总人数呈现逐年下降趋势。矽肺、煤工尘肺接尘工龄MP25P75)分别为4.0(3.0,11.0)年、16.0(10.0,25.0)年。采矿业、小型、私营企业病例最多,分别占59.5%、49.7%、46.6%。矽肺和煤工尘肺10年生存率分别为65.3%、83.4%,二者生存曲线差异有统计学意义(χ2=30.422,P < 0.05)。

    结论

    重庆市渝北区近年来每年新增职业性尘肺病人数超过10例,矽肺病人生存率不高,形势不容乐观,建议相关部门加强对小型、私有等重点企业的监管,加大尘肺病防治宣教力度,加强对尘肺病人的救助救治。

     

    Abstract: Background

    Pneumoconiosis is the most common and serious occupational disease in China. The incidence of pneumoconiosis is still very high, and there are few reports on its survival analysis.

    Objective

    This study describes the characteristics and analyzes the survival of newly reported pneumoconiosis in Yubei District of Chongqing, and to provide evidence and suggestions for local prevention and treatment of pneumoconiosis.

    Methods

    Through the information system of occupational diseases and health hazards, occupational disease diagnosis and appraisal institutions, and the follow-up survey project of occupational pneumoconiosis in 2020, the data of newly reported pneumoconiosis and its survival in Yubei District of Chongqing from 2006 to 2019 were collected. Chi square test or Fisher exact test were used to compare the differences between silicosis and coal worker's pneumoconiosis in the stages of onset, diagnosis time, and length of service. Kaplan-Meier method was used for survival analysis. Log-rank test was used for survival curve comparison.

    Results

    There were 768 newly reported cases of pneumoconiosis in Yubei District from 2006 to 2019. The median age (P25, P75) at diagnosis was 57 (50, 64) years. Most of them were male (99.9%) and coal worker's pneumoconiosis (54.0%). The incidence peak of newly reported silicosis stage Ⅰ, Ⅱ, and Ⅲ appeared in 2012, and the incidence peak of newly reported coal worker's pneumoconiosis stage Ⅰ appeared in 2015. From 2016 to 2019, the total number of newly reported pneumoconiosis cases showed a downward trend year by year. The median (P25, P75) length of service with dust exposure of the silicosis cases and the coal worker's pneumoconiosis cases were 4.0 (3.0, 11.0) years and 16.0 (10.0, 25.0) years, respectively. Mining industry, small enterprises, and private enterprises had the most pneumoconiosis cases, accounting for 59.5%, 49.7%, and 46.6% of total reported cases respectively. The 10-year survival rates of the silicosis cases and the coal worker's pneumoconiosis cases were 65.3% and 83.4% respectively, and the difference of survival curve between them was statistically significant (χ2=30.422, P < 0.05).

    Conclusion

    In recent years, there are more than 10 newly reported cases of occupational pneumoconiosis every year, and the survival rate of silicosis patients is still low in Yubei District of Chongqing. The overall pneumoconiosis situation is far from optimistic. It is suggested that relevant departments strengthen the supervision of small, private, and other key enterprises, the advocacy of pneumoconiosis prevention and treatment, and the rescue and treatment of pneumoconiosis patients.

     

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