噪声对糖脂代谢影响的研究进展

Research progress on potential effects of noise on glycolipid metabolism

  • 摘要: 噪声污染问题已成为普遍存在的公共卫生问题。噪声暴露对人体健康的危害不容忽视。噪声暴露不仅损害听觉系统,还对非听觉系统有影响。目前,国内外越来越多流行病学研究表明噪声暴露可能与糖脂代谢紊乱相关。本文主要总结了近年来国内外有关噪声暴露与糖脂代谢紊乱相关的疾病(如2型糖尿病、肥胖、代谢综合征和高脂血症等)关联的流行病学证据;并从目前研究较为清晰的应激源、睡眠障碍以及肠道菌群调节机制介绍噪声暴露对糖脂代谢影响的生物学机制。本文拟通过探讨噪声暴露对糖脂代谢相关疾病的影响,为进一步确定噪声相关危险因素,开展后续相关研究以及制定科学有效的防控措施提供依据。

     

    Abstract: Noise pollution has become a common public health problem. The harm of noise exposure to human health cannot be ignored. Exposure to noise not only damages the auditory system but also affects the non-auditory system. At present, accumulating domestic and international epidemiological studies have suggested that noise exposure may be related to glycolipid metabolism disturbance. This article summarized recent epidemiological evidence of the association between noise exposure and glucose and lipid metabolism disorders, such as type 2 diabetes, obesity, metabolic syndrome, and hyperlipidaemia. The potential biological mechanisms connecting noise exposure to glucolipid metabolism were also introduced, e.g. noise as a stressor, sleep disorders, and intestinal flora regulation. This study discussed the impacts of noise exposure on glycolipid metabolism related diseases, providing a basis for further identifying noise related risk factors, conducting future related research, and formulating scientific and effective prevention and control measures.

     

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